| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-VTI1B (C-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | VTI1B |
| Gene ID: | 10490 |
| Uniprot ID: | VTI1B_HUMAN |
| Immunogen Region: | C-Term |
| Specificity: | Specific for VTI1B. |
| Immunogen: | A synthetic peptide from the c-terminal region of human VTI1B conjugated to an immunogenic carrier protein was used as the antigen. |
| Function | V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. |
| Protein Name | Vesicle Transport Through Interaction With T-Snares Homolog 1b Vesicle Transport V-Snare Protein Vti1-Like 1 Vti1-Rp1 |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | Early Endosome Membrane Single-Pass Type Iv Membrane Protein Late Endosome Membrane Lysosome Membrane Cytoplasmic Granule Recycling Endosome Membrane |
| Alternative Antibody Names | Anti-Vesicle Transport Through Interaction With T-Snares Homolog 1b antibody Anti-Vesicle Transport V-Snare Protein Vti1-Like 1 antibody Anti-Vti1-Rp1 antibody Anti-VTI1B antibody Anti-VTI1 antibody Anti-VTI1L antibody Anti-VTI1L1 antibody Anti-VTI2 antibody |
Information sourced from Uniprot.org