Human CCL8/MCP-2 protein (Recombinant) (N-hFC) (STJP002859)

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STJP002859
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Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CCL8/MCP-2-N-hFC protein was developed from hek293 cells and has a target region of N-hFC. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CCL8
Gene ID: 6355
Uniprot ID: CCL8_HUMAN
Immunogen Region: Gln24-Pro99
Immunogen: Recombinant Human CCL8/MCP-2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln24-Pro99) of human CCL8/MCP-2 (Accession #NP_005614.2) fused with and a hFc tag at the N-terminus.
Post Translational Modifications N-terminal processed form MCP-2(6-76) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.
Function Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.
Protein Name C-C Motif Chemokine 8
Hc14
Monocyte Chemoattractant Protein 2
Monocyte Chemotactic Protein 2
Mcp-2
Small-Inducible Cytokine A8 Cleaved Into - Mcp-2(6-76
Cellular Localisation Secreted
Alternative Protein Names C-C Motif Chemokine 8 protein
Hc14 protein
Monocyte Chemoattractant Protein 2 protein
Monocyte Chemotactic Protein 2 protein
Mcp-2 protein
Small-Inducible Cytokine A8 Cleaved Into - Mcp-2(6-76 protein
CCL8 protein
MCP2 protein
SCYA10 protein
SCYA8 protein

Information sourced from Uniprot.org

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